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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR2C1 All Species: 9.09
Human Site: T379 Identified Species: 16.67
UniProt: P13056 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13056 NP_001027458.1 603 67315 T379 S H V A F R L T M P S P M P E
Chimpanzee Pan troglodytes XP_001137621 678 75113 T454 S H V A F R L T M P S P M P E
Rhesus Macaque Macaca mulatta XP_001107297 554 61731 E336 A K A L N P G E S T A C Q S S
Dog Lupus familis XP_854792 605 67422 L380 D S H V A F R L T M P S P M P
Cat Felis silvestris
Mouse Mus musculus Q505F1 590 65487 M371 R L T M P S P M P E Y L N V H
Rat Rattus norvegicus Q8VIJ4 590 65509 M371 R L T M P S P M P E Y L N V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510105 561 61971 P343 L T M P S P M P E Y L N V H Y
Chicken Gallus gallus O42101 501 57084 M283 P Q V Q A K I M A Y L Q Q E Q
Frog Xenopus laevis Q66J63 637 70793 T413 V H I A F R L T M P S P M P E
Zebra Danio Brachydanio rerio Q06725 411 45463 Y193 E P Y P T S R Y G S Q C M Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16375 543 57969 R325 A E P Y P T S R Y G Q C M Q P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4B8 615 68010 K372 F L T V H F V K D S R V S L R
Sea Urchin Strong. purpuratus Q26622 583 63834 H364 M P Q F L N V H Y I C E S A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 90.3 96 N.A. 87.5 87.5 N.A. 77.7 21.5 72.6 27 N.A. 22 N.A. 22.9 49
Protein Similarity: 100 87.6 91.2 97.6 N.A. 92.2 91.7 N.A. 84.7 40.9 82.7 42.7 N.A. 37.8 N.A. 42.1 65.1
P-Site Identity: 100 100 0 0 N.A. 0 0 N.A. 0 6.6 86.6 6.6 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 100 13.3 0 N.A. 0 0 N.A. 20 26.6 93.3 6.6 N.A. 13.3 N.A. 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 8 24 16 0 0 0 8 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 24 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 8 8 0 0 0 0 0 8 8 16 0 8 0 8 24 % E
% Phe: 8 0 0 8 24 16 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 8 8 0 0 0 0 0 % G
% His: 0 24 8 0 8 0 0 8 0 0 0 0 0 8 16 % H
% Ile: 0 0 8 0 0 0 8 0 0 8 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 24 0 8 8 0 24 8 0 0 16 16 0 8 0 % L
% Met: 8 0 8 16 0 0 8 24 24 8 0 0 39 8 0 % M
% Asn: 0 0 0 0 8 8 0 0 0 0 0 8 16 0 0 % N
% Pro: 8 16 8 16 24 16 16 8 16 24 8 24 8 24 24 % P
% Gln: 0 8 8 8 0 0 0 0 0 0 16 8 16 16 8 % Q
% Arg: 16 0 0 0 0 24 16 8 0 0 8 0 0 0 8 % R
% Ser: 16 8 0 0 8 24 8 0 8 16 24 8 16 8 16 % S
% Thr: 0 8 24 0 8 8 0 24 8 8 0 0 0 0 0 % T
% Val: 8 0 24 16 0 0 16 0 0 0 0 8 8 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 0 8 16 16 16 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _